Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | 4,6,8-Trichloro-2-methylquinoline | HCID 282966 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 14837827 | HCID 14837827 | 93% |
Reaction Steps
A mixture of 2.46 g of 2-methyl-4,6,8-trichloro-quinoline, 1.82 g of the sodium salt of 1,2,4-triazole and 10 ml of dimethyl formamide is stirred at 100° C. for 25 hours whereupon the reaction mixture is poured into 100 ml of water. The precipitated product is filtered. Thus 2.59 g of the desired compound are obtained, yield 93%. Mp.: 220°-222° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05104884 |
|---|
| Source dataset | uspto-grants-1992_04 |
|---|
| ORD ID | ord-21c07925908545599dead439afdcb8ae |
|---|
| Source note | uspto-grants-1992_04 |
|---|
