反应详情

温度

100 °C

A mixture of 1.78 g of 2-chloro-4-methyl-quinoline, 0.76 g of 1,2,4-triazole and 10 ml of chloro benzene is stirred at 100° C. for 7 hours. The reaction mixture is cooled, the precipitated product is filtered, dissolved in 5 ml of ethanol and precipitated by adding 10 ml of ethyl ether. The precipitated product is filtered. Thus 1.72 g of the desired compound are obtained, yield 70%. Mp.: 193°-194° C.

1. temperatureThe reaction mixture is cooled
2. filtrationthe precipitated product is filtered
3. dissolutiondissolved in 5 ml of ethanol
4. customprecipitated
5. additionby adding 10 ml of ethyl ether
6. filtrationThe precipitated product is filtered