Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 19822132 | HCID 19822132 | — |
| Reactant | HCID 178433329 | HCID 178433329 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 14837869 | HCID 14837869 | 62% |
Reaction Steps
A mixture of 3.99 g of 2-chloro-4,6-bis-trichloromethyl-quinoline, 1.26 g of the sodium salt of 3-methyl-1,2,4-triazole and 10 ml of dimethyl formamide is stirred at 100° C. for 20 hours. The reaction mixture is poured into 100 ml of water, the precipitated product is filtered and recrystallized from 10 ml of ethanol. Thus 2.76 g of the desired compound are obtained, yield 62%. M.p.: 169°-170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05104884 |
|---|
| Source dataset | uspto-grants-1992_04 |
|---|
| ORD ID | ord-3837a4f61e554b6e8c5a376bb24a1589 |
|---|
| Source note | uspto-grants-1992_04 |
|---|
