Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 4,5-Dichloro-2,8-dimethylquinoline | HCID 16642490 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 14837829 | HCID 14837829 | 77.4% |
Reaction Steps
A mixture of 2.26 g of 4,5-dichloro-2,8-dimethyl-quinoline, 1.38 g of 1,2,4-triazole and 0.1 g of 96% sulfuric acid is stirred at 70° C. for 3 hours. The reaction mixture is poured into 50 ml of water and neutralized with 1 ml of a concentrated ammonium hydroxide solution. The precipitated product is filtered and washed with water. Thus 2.0 g of the desired compound are obtained, yield 77.4%. Mp.: 117°-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05104884 |
|---|
| Source dataset | uspto-grants-1992_04 |
|---|
| ORD ID | ord-53a3ea13bf1a424c975cd904adf93105 |
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| Source note | uspto-grants-1992_04 |
|---|
