Sulfuric Acid → HCID 14837829, compound

HRID 1030108Notes

Reaction equation

HRID 1030108 reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([CH3:13])[CH:8]=[CH:9][C:10]=2[Cl:12])[N:5]=[C:4]([CH3:14])[CH:3]=1.[NH:15]1[CH:19]=[N:18][CH:17]=[N:16]1.S(=O)(=O)(O)O.[OH-].[NH4+]>O>[N:15]1([C:2]2[C:11]3[C:6](=[C:7]([CH3:13])[CH:8]=[CH:9][C:10]=3[Cl:12])[N:5]=[C:4]([CH3:14])[CH:3]=2)[CH:19]=[N:18][CH:17]=[N:16]1

Participants

6

Reactant 4

HCID 1118Sulfuric AcidHCID 92571H-1,2,4-TriazoleHCID 14923Ammonium HydroxideHCID 166424904,5-Dichloro-2,8-dimethylquinoline

Product 1

HCID 14837829HCID 14837829, compoundYield 77.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
70 °C

Procedure

A mixture of 2.26 g of 4,5-dichloro-2,8-dimethyl-quinoline, 1.38 g of 1,2,4-triazole and 0.1 g of 96% sulfuric acid is stirred at 70° C. for 3 hours. The reaction mixture is poured into 50 ml of water and neutralized with 1 ml of a concentrated ammonium hydroxide solution. The precipitated product is filtered and washed with water. Thus 2.0 g of the desired compound are obtained, yield 77.4%. Mp.: 117°-118° C.

Workup

  1. filtrationThe precipitated product is filtered
  2. washwashed with water

Sources & evidence

ORD record
ord-53a3ea13bf1a424c975cd904adf93105
Source dataset
uspto-grants-1992_04
Patent number
US05104884

Reaction notes

Loading…