Dibromodifluoromethane → HCID 67826226, compound

HRID 1030333Notes

Reaction equation

HRID 1030333 reaction equation
FF.[CH2:3]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1O)[CH:4]=[CH2:5].[OH-:13].[K+].[Br:15][C:16](Br)([F:18])[F:17]>CN(C)C=O>[Br:15][C:16]([F:18])([F:17])[O:13][CH:5]=[CH:4][CH2:3][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

6

Reactant 4

HCID 6382DibromodifluoromethaneHCID 14797Potassium HydroxideHCID 156242-Allylphenol2×HCID 24524Fluorine

Product 1

HCID 67826226HCID 67826226, compoundYield 9%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

According to the Journal of Fluorine Chemistry, 20, 765 (1982), o-allylphenol is dissolved in dimethylformamide, an equimolar amount of potassium hydroxide and a catalytic amount of 18-crownether-6 are added and then 2 moles of dibromodifluoromethane per mole of o-allylphenol is added. The mixture is reacted to obtain the corresponding o-(bromodifluoromethoxy)allylbenzene in a 9% yield.

Workup

  1. customThe mixture is reacted

Sources & evidence

ORD record
ord-ea2aa48655ec4e59884953f5c1403205
Source dataset
uspto-grants-1992_04
Patent number
US05105021

Reaction notes

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