Hydrochloric Acid → HCID 73654795, compound

HRID 1030394Notes

Reaction equation

HRID 1030394 reaction equation
C([O:5][C:6]([CH2:8][O:9][C:10]1[C:11]([CH3:57])=[C:12]2[C:17](=[C:18]([CH3:21])[C:19]=1[CH3:20])[O:16][C:15]([CH2:23][O:24][C:25]1[CH:54]=[CH:53][C:28]([CH2:29][C:30]3([CH2:45][C:46]([O:48]C(C)(C)C)=[O:47])[S:34][C:33](=[O:35])[N:32]([CH2:36][C:37]([O:39]C(C)(C)C)=[O:38])[C:31]3=[O:44])=[CH:27][CH:26]=1)([CH3:22])[CH2:14][C:13]2=[N:55][OH:56])=[O:7])(C)(C)C.Cl>O1CCOCC1>[C:6]([CH2:8][O:9][C:10]1[C:11]([CH3:57])=[C:12]2[C:17](=[C:18]([CH3:21])[C:19]=1[CH3:20])[O:16][C:15]([CH2:23][O:24][C:25]1[CH:26]=[CH:27][C:28]([CH2:29][C:30]3([CH2:45][C:46]([OH:48])=[O:47])[S:34][C:33](=[O:35])[N:32]([CH2:36][C:37]([OH:39])=[O:38])[C:31]3=[O:44])=[CH:53][CH:54]=1)([CH3:22])[CH2:14][C:13]2=[N:55][OH:56])([OH:7])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 73654796HCID 73654796, compound

Product 1

HCID 73654795HCID 73654795, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 270 mg of di-t-butyl α,α'-{5-[4-(6-t-butoxycarbonylmethoxy-4-hydroxyimino -2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl]-2,4-dioxothiazolidine-3,5-diyl}diacetate (prepared as described in Example 56) and 3 ml of a 4N dioxane solution of hydrogen chloride was treated in the same manner described in Example 61, to give the title compound as a pale yellow powder, softening at 90°-100° C.

Workup

  1. additionwas treated in the same manner

Sources & evidence

ORD record
ord-a7b29bf885b44aad98d48be525bbb8e7
Source dataset
uspto-grants-1992_04
Patent number
US05104888

Reaction notes

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