Tetrahydrofuran → HCID 19822248, compound

HRID 1030417Notes

Reaction equation

HRID 1030417 reaction equation
[C:1]([O:4][C:5]1[C:6]([CH3:30])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([OH:28])([CH2:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([N+:25]([O-])=O)=[CH:21][CH:20]=1)[CH2:9][C:8]2=[O:29])(=[O:3])[CH3:2].O1CCCC1>[Pd].C(O)C>[C:1]([O:4][C:5]1[C:6]([CH3:30])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([CH2:17][O:18][C:19]1[CH:20]=[CH:21][C:22]([NH2:25])=[CH:23][CH:24]=1)([OH:28])[CH2:9][C:8]2=[O:29])(=[O:3])[CH3:2]

Participants

5

Reactant 2

HCID 8028TetrahydrofuranHCID 19822217HCID 19822217, compound

Product 1

HCID 19822248HCID 19822248, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Following the same procedure as described in Preparation 24, 7 g of 6-acetoxy-2-hydroxy-5,7,8-trimethyl-2-(4-nitrophenoxymethyl)chroman-4-one (prepared as described in Preparation 43) were treated with 5 g of 10% w/w palladium-on-carbon, 100 ml of tetrahydrofuran and 100 ml of ethanol, to give the title compound.

Sources & evidence

ORD record
ord-e44661b2efb74aacadce5beca2361fd2
Source dataset
uspto-grants-1992_04
Patent number
US05104888

Reaction notes

Loading…