Hydrochloric Acid → HCID 131717311, compound

Participants

Reaction Conditions

Reaction Steps

α,α-Diethoxymethyl-β-tert-butoxycarbonylamino-3,5-dimethoxy-benzenepropanol (200 g) was dissolved in aqueous 37% hydrochloric acid (20 ml) cooled at 0° C. The resulting red solution was warmed at 100° C. for 3 minutes and then immediate ly cooled at 0° C. Evaporation of the reaction mixture yielded a brown solid which was recrystallized from an ethyl acetate/methanol mixture to give the title compound as a brown solid (101 mg).

Provenance & Evidence