m-Chloroperbenzoic acid → HCID 14839450, compound

HRID 1030806Notes

Reaction equation

HRID 1030806 reaction equation
[CH:1]1([NH:6][C:7]2[CH:23]=[CH:22][CH:21]=[CH:20][C:8]=2[CH2:9][S:10][C:11]2[NH:12][C:13]3[C:14]([N:19]=2)=[N:15][CH:16]=[CH:17][CH:18]=3)[CH2:5][CH2:4][CH2:3][CH2:2]1.ClC1C=CC=C(C(OO)=[O:32])C=1>C(Cl)(Cl)Cl>[CH:1]1([NH:6][C:7]2[CH:23]=[CH:22][CH:21]=[CH:20][C:8]=2[CH2:9][S:10]([C:11]2[NH:12][C:13]3[C:14]([N:19]=2)=[N:15][CH:16]=[CH:17][CH:18]=3)=[O:32])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 14839449HCID 14839449, compound

Product 1

HCID 14839450HCID 14839450, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

2-Mercaptoimidazo[4,5-b]pyridine and 2-(N-cyclopentylamino)benzyl chloride hydrochloride were reacted in an aqueous ethanol solution to obtain 2-[2-(N-cyclopentylamino)benzylthio]-imidazo[4,5-b]pyridine in the same manner as in Example 9-(2). The obtained 2-[2-(N-cyclopentylamino)benzylthio]imidazo[4,5-b]pyridine was oxidized by m-chloroperbenzoic acid in chloroform in the same manner as in Example 9-(3) to give 2-[2-(N-cyclopentylamino)benzylsulfinyl]imidazo[4,5-b]pyridine as a pale yellow crystalline product. m.p.: 134° C. (decompn.)

Sources & evidence

ORD record
ord-7b97ea341bd146eaac3edd160dd90e0a
Source dataset
uspto-grants-1992_04
Patent number
US05106976

Reaction notes

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