反应详情

7.5 g of the 4-dodecylphenol obtained in (1) above was dissolved in 25 ml of acetic acid and 12.6 ml of 30% aqueous nitric acid solution was dropwise added slowly to the resulting solution, and then the resulting mixture was subjected to reaction at about 10° C. for one hour. The reaction mixture was added to 35 g of ice water and the extraction with 35 ml of diethyl ether was conducted three times. The diethyl ether layer thus obtained was washed with 35 ml of 5% aqueous NaHCO solution, and then dried with MgSO4. Subsequently, the solvent was distilled off to obtain 5.93 g of 4-dodecyl-2-nitrophenol.

1. customthe resulting mixture was subjected to reaction at about 10° C. for one hour
2. extractionthe extraction with 35 ml of diethyl ether
3. customThe diethyl ether layer thus obtained
4. washwas washed with 35 ml of 5% aqueous NaHCO solution
5. dry with materialdried with MgSO4
6. distillationSubsequently, the solvent was distilled off