Methylhydrazine → HCID 19025387, compound

HRID 1030975Notes

Reaction equation

HRID 1030975 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]=[C:11]=[S:12])=[CH:6][CH:5]=1)[CH3:2].[CH3:13][NH:14][NH2:15]>C(O)C>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[S:12])[N:14]([CH3:13])[NH2:15])=[CH:6][CH:5]=1)[CH3:2]

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 77006p-Ethoxyphenyl isothiocyanate

Product 1

HCID 19025387HCID 19025387, compoundYield 79.5%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following procedures similar to those employed in Step A of Example 2, the reaction of 2.5 g (0.0698 mole) of 4-ethoxyphenyl isothiocyanate and 3.22 g (0.0698 mole) of methylhydrazine in 100 ml of ethanol yielded 12.5 g of 4-(4-ethoxyphenyl)-2-methyl-3-thiosemicarbazide as a solid. The nmr spectrum was consistent with the proposed structure.

Sources & evidence

ORD record
ord-7350fbacbfcc40959fdb960bbc440c53
Source dataset
uspto-grants-1992_04
Patent number
US05108486

Reaction notes

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