Hydrochloric Acid → HCID 22402938, compound

HRID 1031011Notes

Reaction equation

HRID 1031011 reaction equation
[CH3:1][N:2]1[C:6]2=[CH:7][CH:8]=[C:9]([C:15]([O:17]C)=[O:16])[C:10]([C:11]([O:13]C)=[O:12])=[C:5]2[N:4]=[C:3]1[CH3:19].[OH-].[Na+].Cl>>[CH3:1][N:2]1[C:6]2=[CH:7][CH:8]=[C:9]([C:15]([OH:17])=[O:16])[C:10]([C:11]([OH:13])=[O:12])=[C:5]2[N:4]=[C:3]1[CH3:19]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 22402970HCID 22402970, compound

Product 1

HCID 22402938HCID 22402938, compoundYield 86.8%

Conditions

Temperature
100 °C

Procedure

A mixture of dimethyl 1,2-dimethyl-4,5-benzimidazoledicarboxylate (1.70 g, 6.49 mmol) and 2N sodium hydroxide (25 mL, 12.5 mmol) is stirred for 5 hours at 100° C. The mixture is cooled, acidified to pH 4 with hydrochloric acid and filtered to afford the title product as a white powder (1.32 g, 86.8%), mp 305°-308° C. (dec).

Workup

  1. temperatureThe mixture is cooled
  2. filtrationfiltered

Sources & evidence

ORD record
ord-679ab23d50b9424d858a1195c6ae8249
Source dataset
uspto-grants-1992_04
Patent number
US05108485

Reaction notes

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