HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Dithionite → 2-Methyl-4-nitroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | benzyl N-(2-methyl-4-nitrophenyl)carbamate | HCID 305261 | — |
| Product | 2-Methyl-4-nitroaniline | HCID 7441 | — |
Reaction Steps
Analogously to Example 7a), from 50 g. 2-methyl-4-nitroaniline is prepared 81.3 g. (88% of theory) N-benzyloxycarbonyl-2-methyl-4-nitroaniline which is reduced with sodium dithionite to give 44 g. 4-benzyloxycarbonylamido-3-methylaniline; m.p. 60°-62° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05108890 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-129883c42c224d9ab99c2f2ec42adb91 |
| Source note | uspto-grants-1992_04 |