反应详情

Diaminomaleonitrile (26.2 g]was added in portions to a solution containing cyanogen chloride (14.9 g) in tetrahydrofuran (200 ml). The mixture was then warmed to room temperature and finally heated under reflux for 1 hour. The resulting brown solid was collected by filtration and washed with a solution of sodium acetate. The remaining solid was dissolved in a sodium bicarbonate solution and treated with charcoal, filtered and acidified to give 2-amino-4,5-dicyanoimidazole, m.p. 276°-278°.

1. temperaturefinally heated
2. temperatureunder reflux for 1 hour
3. filtrationThe resulting brown solid was collected by filtration
4. washwashed with a solution of sodium acetate
5. dissolutionThe remaining solid was dissolved in a sodium bicarbonate solution
6. additiontreated with charcoal
7. filtrationfiltered