Benzaldehyde → HCID 67946032, compound

HRID 1031234Notes

Reaction equation

[ClH:1].[NH:2]1[C:10]23[CH2:11][CH2:12][CH2:13][CH2:14][C:5]2([CH2:6][CH2:7][C:8]2[CH:18]=[CH:17][CH:16]=[CH:15][C:9]=23)[CH2:4][CH2:3]1.[CH:19](=O)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[ClH:1].[C:20]1([CH2:19][N:2]2[C:10]34[CH2:11][CH2:12][CH2:13][CH2:14][C:5]3([CH2:6][CH2:7][C:8]3[CH:18]=[CH:17][CH:16]=[CH:15][C:9]=34)[CH2:4][CH2:3]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 67946049HCID 67946049, compound

Product 1

HCID 67946032HCID 67946032, compoundYield 42%

Procedure

In a manner similar to that described in Example 32, the product from Example 23 (0.34 g, 1.50 mmol) and benzaldehyde are reacted. Workup, followed crystallization from ether and HCl gave the title compound (0.22 g, 42%) as a white solid mp 235°-237° C.

Workup

customcrystallization from ether and HCl

Sources & evidence

ORD record: ord-68d8b008d12f4646ae8a05f6838eeb4f
Source dataset: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05109136

Reaction notes

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