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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031282Generated: October 29, 2026

Ammonia → P-Toluenesulfonamide

https://huagongshe.com/reaction/1031282

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant4-Toluenesulfonyl chlorideHCID 7397—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
ProductP-ToluenesulfonamideHCID 6269100%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-2642c201402c40cba165d232e657aa90
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"