Ammonia → P-Toluenesulfonamide

HRID 1031282Notes

Reaction equation

HRID 1031282 reaction equation
Cc1ccc(S(=O)(=O)Cl)cc1.N>CC(C)=O.O.O=C([O-])O.OCCOCCOCCOCCOCCO.[Na+]>Cc1ccc(S(N)(=O)=O)cc1

Participants

7

Reactant 2

HCID 222AmmoniaHCID 73974-Toluenesulfonyl chloride

Product 1

HCID 6269P-ToluenesulfonamideYield 100%

Reagents, catalysts & solvents 4

HCID 516892Sodium BicarbonateReagentHCID 180AcetoneSolventHCID 962WaterSolventHCID 62551Pentaethylene glycolSolvent

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded
  2. extractionKeep organic
  3. washNo procedure recorded
  4. washNo procedure recorded
  5. dry with materialNo procedure recorded
  6. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-2642c201402c40cba165d232e657aa90
Source dataset
39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
Original link
View source

Reaction notes

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