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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031285Generated: October 29, 2026

4-Toluenesulfonyl chloride → Benzenesulfonamide, N-(3-(dimethylamino)propyl)-4-methyl- (9CI)

https://huagongshe.com/reaction/1031285

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
ReactantN,N-Dimethyl-1,3-propanediamineHCID 7993—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
ProductBenzenesulfonamide, N-(3-(dimethylamino)propyl)-4-methyl- (9CI)HCID 20237592%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-be98f79220f8485aaa48ed9e41c171ae
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"