4-Toluenesulfonyl chloride → Benzenesulfonamide, N-(3-(dimethylamino)propyl)-4-methyl- (9CI)

HRID 1031285Notes

Reaction equation

HRID 1031285 reaction equation
CN(C)CCCN.Cc1ccc(S(=O)(=O)Cl)cc1>CC(C)=O.O.O=C([O-])O.OCCOCCOCCOCCOCCO.[Na+]>Cc1ccc(S(=O)(=O)NCCCN(C)C)cc1

Participants

7

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 7993N,N-Dimethyl-1,3-propanediamine

Product 1

HCID 202375Benzenesulfonamide, N-(3-(dimethylamino)propyl)-4-methyl- (9CI)Yield 92%

Reagents, catalysts & solvents 4

HCID 516892Sodium BicarbonateReagentHCID 180AcetoneSolventHCID 962WaterSolventHCID 62551Pentaethylene glycolSolvent

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded
  2. extractionKeep organic
  3. washNo procedure recorded
  4. washNo procedure recorded
  5. dry with materialNo procedure recorded
  6. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-be98f79220f8485aaa48ed9e41c171ae
Source dataset
39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
Original link
View source

Reaction notes

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