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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031292Generated: October 29, 2026

Aniline → 4-Nitro-N-phenylbenzenesulfonamide

https://huagongshe.com/reaction/1031292

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant4-Nitrobenzenesulfonyl chlorideHCID 7404—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
Product4-Nitro-N-phenylbenzenesulfonamideHCID 31372198%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-2d9744b45378425790df1ae6c2ee2c57
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"