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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031295Generated: October 29, 2026

4-Nitrobenzenesulfonyl chloride → N-benzyl-4-nitrobenzenesulfonamide

https://huagongshe.com/reaction/1031295

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzenesulfonyl chlorideHCID 7404—
ReactantBenzylamineHCID 7504—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
ProductN-benzyl-4-nitrobenzenesulfonamideHCID 745343100%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-460799004ab944a2a387bfaf2dda9bb0
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"