4-Nitrobenzenesulfonyl chloride → N-benzyl-4-nitrobenzenesulfonamide

HRID 1031295Notes

Reaction equation

HRID 1031295 reaction equation
NCc1ccccc1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>CC(C)=O.O.O=C([O-])O.OCCOCCOCCOCCOCCO.[Na+]>O=[N+]([O-])c1ccc(S(=O)(=O)NCc2ccccc2)cc1

Participants

7

Reactant 2

HCID 74044-Nitrobenzenesulfonyl chlorideHCID 7504Benzylamine

Product 1

HCID 745343N-benzyl-4-nitrobenzenesulfonamideYield 100%

Reagents, catalysts & solvents 4

HCID 516892Sodium BicarbonateReagentHCID 180AcetoneSolventHCID 962WaterSolventHCID 62551Pentaethylene glycolSolvent

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded
  2. extractionKeep organic
  3. washNo procedure recorded
  4. washNo procedure recorded
  5. dry with materialNo procedure recorded
  6. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-460799004ab944a2a387bfaf2dda9bb0
Source dataset
39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
Original link
View source

Reaction notes

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