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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031298Generated: October 30, 2026

P-Anisidine → 4-Acetyl-N-(4-methoxyphenyl)benzenesulfonamide

https://huagongshe.com/reaction/1031298

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant4-Acetylbenzenesulfonyl chlorideHCID 266418—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
Product4-Acetyl-N-(4-methoxyphenyl)benzenesulfonamideHCID 2064047100%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-64b2625cf0d0437d98111a403df2197f
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"