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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031314Generated: November 1, 2026

2-Mesitylenesulfonyl chloride → 1-[(2,4,6-Trimethylphenyl)sulfonyl]-1,2,3,4-tetrahydroquinoline

https://huagongshe.com/reaction/1031314

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Mesitylenesulfonyl chlorideHCID 13046—
Reactant1,2,3,4-TetrahydroquinolineHCID 69460—
ReagentSodium BicarbonateHCID 516892—
SolventAcetoneHCID 180—
SolventWaterHCID 962—
SolventPentaethylene glycolHCID 62551—
Product1-[(2,4,6-Trimethylphenyl)sulfonyl]-1,2,3,4-tetrahydroquinolineHCID 66909386%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/co400012m
Source dataset39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"
ORD IDord-05d160f1b7da441183b9fa501f445612
Source note39 compound library from "Building a Sulfonamide Library by Eco-Friendly Flow Synthesis"