2-Nitrophenol → 2-(3-Chloro-5-trifluoromethyl-2-pyridyloxy)nitrobenzene

HRID 1031395Notes

Reaction equation

HRID 1031395 reaction equation
[Cl:1][C:2]1[C:3](F)=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[N+:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[OH:22])([O-:15])=[O:14]>>[Cl:1][C:2]1[C:3]([O:22][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N+:13]([O-:15])=[O:14])=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1

Participants

3

Reactant 2

HCID 69472-NitrophenolHCID 12680753-Chloro-2-fluoro-5-(trifluoromethyl)pyridine

Product 1

HCID 150175302-(3-Chloro-5-trifluoromethyl-2-pyridyloxy)nitrobenzeneYield 63%

Procedure

This material was prepared in 63% yield from 3-chloro-2-fluoro-5-trifluoromethylpyridine and 2-nitrophenol following the general procedure outlined in Example 104. The product was isolated as an amber oil which was characterized by IR and 1H NMR spectroscopy.

Workup

  1. customThe product was isolated as an amber oil which

Sources & evidence

ORD record
ord-1ca131e423954e45b30491b0ee95ba16
Source dataset
uspto-grants-1990_09
Patent number
US04954163

Reaction notes

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