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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031396Generated: October 27, 2026

1,3-Difluoro-2-nitrobenzene → 2-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

https://huagongshe.com/reaction/1031396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Difluoro-2-nitrobenzeneHCID 87922—
Reactant2-Chloro-4-(trifluoromethyl)phenolHCID 2736603—
Product2-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzeneHCID 5413741447%

Reaction Steps

This material was prepared in 47% yield from 2,6-difluoronitrobenzene and 2-chloro-4-trifluoromethylphenol following the general procedure outlined in Example 104. The product was isolated as an oil which was characterized by IR and 1H NMR spectroscopy.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04954163
Source datasetuspto-grants-1990_09
ORD IDord-d4b3547b567343b3ba507dca6f1263f8
Source noteuspto-grants-1990_09