Diethyl Oxalate → HCID 14209967, compound

HRID 1031445Notes

Reaction equation

HRID 1031445 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[NH:8][C:9]3[CH:15]=[C:14]([NH2:16])[C:13]([N+:17]([O-])=O)=[CH:12][C:10]=3[N:11]=2)=[CH:3][CH:2]=1.[C:20](OCC)(=[O:26])[C:21](OCC)=[O:22]>>[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[NH:8][C:9]3=[CH:15][C:14]4[NH:16][C:20](=[O:26])[C:21](=[O:22])[NH:17][C:13]=4[CH:12]=[C:10]3[N:11]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 7268Diethyl OxalateHCID 178507222HCID 178507222, compound

Product 1

HCID 14209967HCID 14209967, compoundYield 45%

Procedure

Analogously to Example 3, from 2-(4-pyridyl)-5-amino-6-nitrobenzimidazole, by hydrogenation and reaction with diethyl oxalate, there was obtained, in a yield of 45% of theory, the title compound; m.p. above 300° C.

Workup

  1. customthere was obtained, in a yield of 45% of theory

Sources & evidence

ORD record
ord-eb6c62636f9f4c8ab15ad8e6a7cb06d8
Source dataset
uspto-grants-1990_09
Patent number
US04954498

Reaction notes

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