Water → HCID 14459480, compound

Participants

Reaction Steps

0.70 g (4.1 mmol) of 4-methoxybenzoyl chloride is added to a slurry of 1.0 g (3.15 mmol) of 6-[3-nitro-4-(1-piperazinyl)-phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone and 1.14 ml (8.2 mmol) of triethylamine in 40 ml of 1,2-dichloroethane and the reaction mixture is boiled under reflux for 0.5 h. It is then cooled to room temperature, 50 ml of water are added, and the organic phase is separated off.

Provenance & Evidence