Piperazine → HCID 14459472, compound

HRID 1031467Notes

Reaction equation

HRID 1031467 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH2:9][CH2:10][C:11](=[O:14])[NH:12][N:13]=2)=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].[NH:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1>>[N+:15]([C:3]1[CH:4]=[C:5]([C:8]2[CH2:9][CH2:10][C:11](=[O:14])[NH:12][N:13]=2)[CH:6]=[CH:7][C:2]=1[N:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1)([O-:17])=[O:16]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 14459456HCID 14459456, compound

Product 1

HCID 14459472HCID 14459472, compound

Procedure

10.0 g (39.4 mmol) of 6-(4-chloro-3-nitro-phenyl)-4,5-dihydro-3(2H)-pyridazinone are boiled under reflux with 10.2 g (118.2 mmol) of piperazine for 5 hours.

Sources & evidence

ORD record
ord-304280a6d9ec40bb9587ab2f250a99b1
Source dataset
uspto-grants-1990_09
Patent number
US04954501

Reaction notes

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