Piperazine → HCID 14459474, compound

HRID 1031472Notes

Reaction equation

Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]([CH2:15][OH:16])[CH2:10][C:11](=[O:14])[NH:12][N:13]=2)=[CH:4][C:3]=1[N+:17]([O-:19])=[O:18].[NH:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[N+:17]([C:3]1[CH:4]=[C:5]([C:8]2[CH:9]([CH2:15][OH:16])[CH2:10][C:11](=[O:14])[NH:12][N:13]=2)[CH:6]=[CH:7][C:2]=1[N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1)([O-:19])=[O:18]

Participants

Reactant 2

HCID 4837Piperazine

HCID 14459457HCID 14459457, compound

Product 1

HCID 14459474HCID 14459474, compound

Procedure

19.86 g (0.07 mol) of 6-(4-chloro-3-nitro-phenyl)-4,5-dihydro-5-hydroxymethyl-3(2H)-pyridazinone are reacted with 18.1 g (0.21 mol) of piperazine in a manner analogous to Example 1.

Sources & evidence

ORD record: ord-fa6f6b6af0b34b4d8e6c7520c5dc3650
Source dataset: uspto-grants-1990_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04954501

Reaction notes

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