1-Piperazinecarboxylic acid, ethyl ester → HCID 14459475, compound

Participants

Reaction Steps

1.5 g (6.1 mmol) of the chlorocyanophenylpyridazinone from stage (a) and 5 ml of 1-ethoxycarbonylpiperazine are together heated to 170° C. for 5 hours. After the reaction mixture has cooled, it is poured out on water and extracted with ethyl acetate and the combined organic phases are concentrated by evaporation under vacuum.

Provenance & Evidence