Piperazine → HCID 14459476, compound

HRID 1031475Notes

Reaction equation

HRID 1031475 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]([CH3:15])[CH2:10][C:11](=[O:14])[NH:12][N:13]=2)=[CH:4][C:3]=1[C:16]#[N:17].[NH:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1>>[C:16]([C:3]1[CH:4]=[C:5]([C:8]2[CH:9]([CH3:15])[CH2:10][C:11](=[O:14])[NH:12][N:13]=2)[CH:6]=[CH:7][C:2]=1[N:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1)#[N:17]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 14459458HCID 14459458, compound

Product 1

HCID 14459476HCID 14459476, compound

Procedure

10.0 g (40.4 mmol) of 6-(4-chloro-3-cyano-phenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone are reacted with 10 g of piperazine in a manner analogous to Example 1.

Sources & evidence

ORD record
ord-3b4806846e454a0ea2959feb192b355f
Source dataset
uspto-grants-1990_09
Patent number
US04954501

Reaction notes

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