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HRID1031506

反应详情

EQUATION

反应方程式

HRID 1031506 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CCOP(=O)(CC(=O)N1CCOCC1)OCC
HCID11207805

Phosphonic acid, [2-(4-morpholinyl)-2-oxoethyl]-, diethyl ester

C10H20NO5P

结构：COc1ccc(C(=O)c2ccc(N(C)c3ccccc3)nc2)cc1OC
HCID14878865

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(C(=CC(=O)N2CCOCC2)c2ccc(N(C)c3ccccc3)nc2)cc1OC
HCID53937148

未命名化合物

收率 32.1%

PROCEDURE

实验过程

In the same manner as in Example 1, using 5-(3,4-dimethoxybenzoyl)-2-(N-methylanilino)pyridine (500 mg), diethylphosphonoacetic acid morpholide (800 mg) and 60% sodium hydride (150 mg), E-isomer (250 mg) and Z-isomer (212 mg) of 4-[3-(2-(N-methylanilino)-5-pyridyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine (Compound No.62) were obtained.