Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1031506Generated: October 25, 2026

Sodium hydride → HCID 53937148, compound

https://huagongshe.com/reaction/1031506

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
ReactantPhosphonic acid, [2-(4-morpholinyl)-2-oxoethyl]-, diethyl esterHCID 11207805—
ReactantHCID 14878865HCID 14878865—
ProductHCID 53937148HCID 5393714832.1%

Reaction Steps

In the same manner as in Example 1, using 5-(3,4-dimethoxybenzoyl)-2-(N-methylanilino)pyridine (500 mg), diethylphosphonoacetic acid morpholide (800 mg) and 60% sodium hydride (150 mg), E-isomer (250 mg) and Z-isomer (212 mg) of 4-[3-(2-(N-methylanilino)-5-pyridyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine (Compound No.62) were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04954497
Source datasetuspto-grants-1990_09
ORD IDord-60040d8caa1041c58f900df3b01c3d8d
Source noteuspto-grants-1990_09