反应详情

The solution of 4.25 g (10 mmol) of 2-phtalimidomethyl-1,4-di-phenylmethyl piperazine and 1.25 g (25 mmol) of hydrazine monohydrate in 50 ml ethanol was stirred 2 hours under reflux. Insoluble material was filtered off. The ethanol layer was evaporated to dryness to afford a residue taken up in 20 ml ethyl ether, filtered again and evaporated to give 3.0 g of the title compound as an oil.

1. temperatureunder reflux
2. filtrationInsoluble material was filtered off
3. customThe ethanol layer was evaporated to dryness
4. customto afford a residue
5. filtrationfiltered again
6. customevaporated