Hydrogen Bromide → HCID 23128190, compound
Reaction equation
[CH3:1][N:2]([CH2:4][CH:5]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([O:15]C)[CH:13]=2)[CH2:8][CH2:7][NH:6]1)[CH3:3].[BrH:17]>>[BrH:17].[BrH:17].[CH3:3][N:2]([CH2:4][CH:5]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([OH:15])[CH:13]=2)[CH2:8][CH2:7][NH:6]1)[CH3:1]Participants
3
Procedure
1.0 g (4.55 mmoles) of 1-dimethylaminomethyl-7-methoxy-1,2,3,4-tetrahydroisoquinoline was heated two hours at 130° C. with 30 ml of 48% HBr.
Sources & evidence
- ORD record
- ord-73ecbf7bea7448f5bcc6daf417795a25
- Source dataset
- uspto-grants-1990_09
- Patent number
- US04954509
Reaction notes
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