Hydrogen Bromide → HCID 22168030, compound

HRID 1031605Notes

Reaction equation

HRID 1031605 reaction equation
C(O)(=O)C.[N:5]1([CH2:10][CH:11]2[C:20]3[C:15](=[C:16]([O:21]C)[CH:17]=[CH:18][CH:19]=3)[CH2:14][CH2:13][NH:12]2)[CH2:9][CH2:8][CH2:7][CH2:6]1.[BrH:23]>>[BrH:23].[BrH:23].[N:5]1([CH2:10][CH:11]2[C:20]3[C:15](=[C:16]([OH:21])[CH:17]=[CH:18][CH:19]=3)[CH2:14][CH2:13][NH:12]2)[CH2:9][CH2:8][CH2:7][CH2:6]1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 22168042HCID 22168042, compound

Product 1

HCID 22168030HCID 22168030, compound

Procedure

0.66 g (2.15 mmoles) of (+)-1-(pyrrolidin-1-yl)methyl-5-methoxy-1,2,3,4-tetrahydroisoquinoline acetate were heated two hours at 130° C. with 7 ml of 47% HBr solution.

Sources & evidence

ORD record
ord-98df6135120f440ca48f3fada6312468
Source dataset
uspto-grants-1990_09
Patent number
US04954509

Reaction notes

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