Sodium Azide → HCID 53970795, compound

HRID 1031726Notes

Reaction equation

HRID 1031726 reaction equation
[CH3:1][S:2]([NH:5][C:6]1[C:19]([O:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:18][C:9]2[C:10](=[O:17])[CH:11]=[C:12]([C:14](Cl)=[O:15])[O:13][C:8]=2[CH:7]=1)(=[O:4])=[O:3].[N-:27]=[N+:28]=[N-:29].[Na+]>O1CCCC1>[CH3:1][S:2]([NH:5][C:6]1[C:19]([O:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:18][C:9]2[C:10](=[O:17])[CH:11]=[C:12]([C:14]([N:27]=[N+:28]=[N-:29])=[O:15])[O:13][C:8]=2[CH:7]=1)(=[O:4])=[O:3]

Participants

4

Reactant 2

HCID 33557Sodium AzideHCID 54220196HCID 54220196, compound

Product 1

HCID 53970795HCID 53970795, compoundYield 46%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

3.1 g of 7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one-2-carboxylic acid chloride was dissolved in 80 ml of anhydrous tetrahydrofuran. This solution was dropwise added to 10 ml of an aqueous solution containing 1.26 g of sodium azide in 10 minutes at 5°-10° C. The mixture was stirred for 1.5 hours at 10°-20° C. The resulting crystal was collected by filtration to obtain 1.45 g (yield: 46%) of 7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one-2-carboxylic acid azide having a melting point of 146°-149° C. (decomposed).

Workup

  1. filtrationThe resulting crystal was collected by filtration

Sources & evidence

ORD record
ord-b485b778052149d9868b7d3cb463123c
Source dataset
uspto-grants-1990_09
Patent number
US04954518

Reaction notes

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