HCID 13919018, compound → HCID 53802334, compound

Participants

Reaction Steps

Using each of the ruthenium-phosphine complexes obtained in Examples 2 to 16, the asymmetric hydrogenation reaction of (Z)-N-formyl-1-(4-methoxyphenylmethylene)- 3,4,5,6,7,8-hexahydroisoquinoline was carried out in the same reaction procedures as in Use Example 1 to produce (+)-N-formyl-1-(4-methoxyphenylmethylene)-1,2,3,4,5,6,7,8-octahydroisoquinoline. The results are shown in table 2.

Provenance & Evidence