Cysteamine → HCID 17882707, compound

HRID 1031837Notes

Reaction equation

HRID 1031837 reaction equation
[NH2:1][CH2:2][CH2:3][SH:4].[C:5]1(=[O:11])[O:10][CH2:9][CH2:8][CH2:7][CH2:6]1>[Zn].O>[OH:11][CH2:5][CH2:6][CH2:7][CH2:8][C:9]([NH:1][CH2:2][CH2:3][SH:4])=[O:10]

Participants

5

Reactant 2

HCID 6058CysteamineHCID 10953Delta-Valerolactone2×

Product 1

HCID 17882707HCID 17882707, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 962WaterSolvent

Procedure

A mixture, stirred under an inert atmosphere, of 5 g of cysteamine and 6.05 cm3 of δ-valerolactone is brought to a temperature of about 60°-70° C. for 15 hours. The disappearance of the δ-valerolactone is followed by VPC. The reaction mixture is then poured into 100 cm3 of water and 10 g of acid resin, "Dowex 50" and 3 g of zinc powder are added. The resulting mixture is stirred for 4 hours at ambient temperature and then left overnight. The next day the mixture is filtered and the water is evaporated under reduced pressure.

Workup

  1. additionare added
  2. waitleft overnight
  3. filtrationThe next day the mixture is filtered
  4. customthe water is evaporated under reduced pressure

Sources & evidence

ORD record
ord-463484e1dd74499ebd0b867fe46b27c8
Source dataset
uspto-grants-1990_09
Patent number
US04956175

Reaction notes

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