HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14422913, compound → 1-Cyclopropyl-6,8-difluoro-7-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14422913 | HCID 14422913 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | 1-Cyclopropyl-6,8-difluoro-7-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | HCID 13657423 | — |
Reaction Steps
0.5 g of the compound from Example 11 is heated to 240° C. for one hour in 5 ml of diphenyl ether. The residue remaining after distilling off the solvent consists of 0.3 g of crude product of melting point 208°-10° C. Recrystallization from ethanol gives a melting point of 226°-28°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04956465 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-1d37e95ba85d4073845ff7bcabf66e34 |
| Source note | uspto-grants-1990_09 |