Bromopinacolone → HCID 178488981, compound

HRID 1032065Notes

Reaction equation

HRID 1032065 reaction equation
[CH3:1][N:2]([CH3:24])[C:3]1[CH:23]=[CH:22][C:6]([CH:7]=[N:8][N:9]2[CH:13]=[CH:12][N:11]=[C:10]2[C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)=[CH:5][CH:4]=1.[Br:25][CH2:26][C:27](=[O:32])[C:28]([CH3:31])([CH3:30])[CH3:29]>C(#N)C>[Br-:25].[CH3:24][N:2]([CH3:1])[C:3]1[CH:4]=[CH:5][C:6]([CH:7]=[N:8][N+:9]2[CH:13]=[CH:12][N:11]([CH2:26][C:27](=[O:32])[C:28]([CH3:31])([CH3:30])[CH3:29])[C:10]=2[C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)=[CH:22][CH:23]=1

Participants

4

Reactant 2

HCID 21642BromopinacoloneHCID 54562755HCID 54562755, compound

Product 1

HCID 178488981HCID 178488981, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of 160 mg of 1-[[p-(dimethylamino)benzylidene]amino]-2-(p-methoxyphenyl)imidazole and 400 mg of 1-bromo-3,3-dimethyl-2-butanone in 3 ml of acetonitrile is stirred at 60° for 20 hours. The product is removed by filtration and washed with ether. There is obtained 1-[[p-(dimethylamino)benzylidene]amino]-2-(p-methoxyphenyl)-3-(pivaloylmethyl)imidazolium bromide of melting point 262°.

Workup

  1. customThe product is removed by filtration
  2. washwashed with ether

Sources & evidence

ORD record
ord-6a0e47cf24e343e1bb92808ea8e8bd32
Source dataset
uspto-grants-1990_09
Patent number
US04956470

Reaction notes

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