反应详情

Into a reaction vessel equipped with a stirrer, a cooler, an nitrogen gas introducing inlet and a dropping funnel, benzene (288.5 ml) and methacrylamide (49.1 g; 0.577 mol) were charged, and the resulting mixture was heated with reflux. Refluxing and bubbling with nitrogen gas were continued, during which ethoxalyl chloride (78.5 g; 0.577 mol) was dropwise added thereto in 2.5 hours. After the dropwise addition was completed, refluxing was continued for 5 hours. The benzene was distilled off, hydroquinone (0.01 g) was added thereto, and distillation under reduced pressure was carried out to give N-ethoxalylmethacrylamide (45.8 g). Yield, 43%. B.P., 110°-115° C./0.3 mmHg. Refractive index, 1.473.

1. customInto a reaction vessel equipped with a stirrer
2. additiona cooler, an nitrogen gas introducing inlet and a dropping funnel
3. temperaturethe resulting mixture was heated
4. temperaturewith reflux
5. temperatureRefluxing
6. custombubbling with nitrogen gas
7. additionwas dropwise added
8. additionAfter the dropwise addition
9. temperaturerefluxing
10. waitwas continued for 5 hours
11. distillationThe benzene was distilled off
12. additionhydroquinone (0.01 g) was added
13. distillationdistillation under reduced pressure