HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichlorobenzoyl chloride → Benzamide, 2,6-dichloro-N-[[4-(trifluoromethyl)phenyl]methyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichlorobenzoyl chloride | HCID 78392 | — |
| Reactant | 4-(Trifluoromethyl)benzylamine Hydrochloride | HCID 16090351 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Benzamide, 2,6-dichloro-N-[[4-(trifluoromethyl)phenyl]methyl]- | HCID 164153 | — |
Reaction Steps
To 21.1 g (0.1 mole) of 4-trifluoromethylbenzylamine hydrochloride was added 20.9 g (0.10 mole) of 2,6-dichlorobenzoyl chloride in 200 ml of tetrahydrofuran. Then was added in 1 portion 30 ml triethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04957533 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-c7a60bc74be14d2b9d34342a61f22764 |
| Source note | uspto-grants-1990_09 |