Tert-Butylamine → HCID 14851222, compound

HRID 1032236Notes

Reaction equation

HRID 1032236 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6].[Br:14]Br.[C:16](N)([CH3:19])(C)C>>[Br:14][C:3]1[C:2]([OH:1])=[C:10]([N+:11]([O-:13])=[O:12])[CH:9]=[CH:8][C:4]=1[C:5]([O:7][CH2:16][CH3:19])=[O:6]

Participants

4

Reactant 3

HCID 6385Tert-ButylamineHCID 24408BromineHCID 692653-Hydroxy-4-nitrobenzoic acid

Product 1

HCID 14851222HCID 14851222, compoundYield 70.1%

Procedure

A 0.1 mole of the ethyl ester of 3-hydroxy-4-nitrobenzoic acid was monobrominated using the procedure described in Example 1, except only one equivalent of bromine and two equivalents of t-butyl amine were used. This reaction yielded ethyl 2-bromo-3-hydroxy-4-nitrobenzoate in 70.1% yield. It had a melting point of 58°-61° C.

Sources & evidence

ORD record
ord-74fd466058524acfbec314435ca28dba
Source dataset
uspto-grants-1990_09
Patent number
US04957538

Reaction notes

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