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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1032341Generated: October 25, 2026

Potassium Carbonate → HCID 14556316, compound

https://huagongshe.com/reaction/1032341

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant1-Bromo-2-[bis(4-fluorophenyl)methoxy]ethaneHCID 10568186—
Reactant129084-50-0HCID 14556325—
SolventChloroform methanolHCID 21584188—
ProductHCID 14556316HCID 1455631646.5%

Reaction Steps

Proceeding as in Example 9, using 14.8 g (45 mmole) of 1-[bis(4-fluorophenyl)methoxy]-2-bromoethane, 9.4 g (45 mmole) of 3-(3,5-dimethoxyphenyl)pyrrolidine and 12 g (86 mmole) of potassium carbonate, there was obtained after silica gel column chromatography (eluent chloroform-methanol, 9/1), 9.5 g (yield: 46%) of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-3-(3,5-dimethoxy phenyl)pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04957927
Source datasetuspto-grants-1990_09
ORD IDord-ff9f2269694b4e90bb6a06c0516b061b
Source noteuspto-grants-1990_09