Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 2-(4-Methoxybenzene-1-sulfonyl)pyrimidine | HCID 19759059 | — |
| Product | HCID 19759073 | HCID 19759073 | — |
Reaction Steps
A mixture of 4.6×10-3 mol of 2-(4-methoxybenzenesulphonyl)pyrimidine and 10 of 47%-hydrobromic acid was heated for - hour at 90° C. The reaction medium was neutralized to a pH of 7 with an ammonia solution and the pasty residue was extracted with dichloromethane. The organic phase was then dried and evaporated and the residue so provided was purified by chromatography on a silica column using dichloromethane as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04957925 |
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| Source dataset | uspto-grants-1990_09 |
|---|
| ORD ID | ord-28ae75e14d254552a6ecdbc189c54ae3 |
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| Source note | uspto-grants-1990_09 |
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