HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Cyanide → (4-Benzyloxy-3-nitrophenyl)acetonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Cyanide | HCID 8929 | — |
| Edukt | 4-Benzyloxy-3-nitrobenzyl chloride | HCID 13629302 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | (4-Benzyloxy-3-nitrophenyl)acetonitrile | HCID 13629303 | 88,6% |
Reaktionsschritte
111.0 g of 4-benzyloxy-3-nitrobenzyl chloride and 21.6 g of sodium cyanide in 800 ml of dimethyl sulfoxide are stirred for 2.5 hours at 40° C., then poured into 1.6 1 of ice water. The solid product is recrystallized from ethanol, yielding 95.0 g of (4-benzyloxy-3-nitrophenyl)acetonitrile, mp 91°-97° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04958026 |
| Quelldatensatz | uspto-grants-1990_09 |
| ORD ID | ord-190d917ec37c47c98b3d83ba90d14b2b |
| Quellennotiz | uspto-grants-1990_09 |