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HRID1032514

反应详情

EQUATION

反应方程式

HRID 1032514 的结构方程式

REACTANTS

反应物

2
结构：[C-]#N.[Na+]
HCID8929

Sodium cyanide (Na(CN))

CNNa

结构：O=[N+]([O-])c1cc(CCl)ccc1OCc1ccccc1
HCID13629302

未命名化合物

PRODUCTS

生成物

1
结构：N#CCc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1
HCID13629303

未命名化合物

收率 88.6%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

111.0 g of 4-benzyloxy-3-nitrobenzyl chloride and 21.6 g of sodium cyanide in 800 ml of dimethyl sulfoxide are stirred for 2.5 hours at 40° C., then poured into 1.6 1 of ice water. The solid product is recrystallized from ethanol, yielding 95.0 g of (4-benzyloxy-3-nitrophenyl)acetonitrile, mp 91°-97° C.

WORKUP

后处理

  1. customThe solid product is recrystallized from ethanol